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Subject Area

Anesthesiology and Intensive Care

Article Type

Original Study

Abstract

Objectives to examine the significance of mitral valve velocity time integral (MV VTI) & carotid corrected flow time (FTc) in predicting fluid response in cases with undifferentiated shock. Background Echocardiography and resuscitation are crucial techniques for guiding treatment in severely unwell cases. They have the capability to anticipate and evaluate the reaction to fluid resuscitation. Methods In prospective observational research, 90 cases with early shock (less than twenty-four hours duration) who were admitted to critical care unit with persistent vasopressor requirements despite pre-enrolment fluid resuscitation of more than one liter. Blood pressure, pulse rate, left ventricular velocity time integral (LVOT VTI), MV VTI & carotid FTc were recorded before & after passive leg raise (PLR). A patient was classified as volume responder if their LVOT VTI increased by 12% or more after PLR. This was a commonly used test to assess effectiveness of MV VTI & carotid FTc in predicting fluid responsiveness. Results MV-VTI in response to PLR in comparison to LVOT-VTI showed 84% sensitivity, 100 percent specificity, 100 percent positive predictive value, 83.3 percent negative predictive value, with significant difference p less than 0.001 while carotid FTc showed 86% sensitivity, 100% specificity, 100% PPV, 85.1% NPV, p below 0.001. a statistically significant positive relationship was noted among LVOT VTI with both MV VTI before and after PLR test (r=0.836, r=0.822, respectively) and carotid FTc before Conclusion MV VTI and carotid FTc had the potential to become a reliable tool for evaluating fluid responsiveness in shocked cases

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