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Subject Area

Nephrology

Article Type

Original Study

Abstract

Objectives: to delineate the demographic profile of the study cohort, assess preoperative clinical and laboratory parameters, and investigate postoperative electrolyte abnormalities at different time points.

Background: Kidney transplantation is a vital intervention for end-stage renal disease, with postoperative electrolyte abnormalities posing a significant clinical challenge.

Patients and Methods: Eligible participants from the Nasser Institute, meeting inclusion criteria, underwent a thorough assessment of demographics, medical history, and clinical examinations. Laboratory investigations included blood tests and immunological assays. Statistical analysis employed descriptive statistics and correlation analyses.

Results: The study included 41 recipients, with a mean age of 29.63 years (SD±12.40). Within the first month post-operation, 31.7% exhibited hyponatremia, 4.9% had hyperkalemia, 36.6% developed hypomagnesemia, and 46.3% had hypophosphatemia. All cases had hypocalcemia, and metabolic acidosis (pH < 7.35) predominated in 68.3%. At more than a month post-operation, 29.3% had hyponatremia, 24.4% had hyperkalemia, and 19.5% had hypercalcemia. Significant variations in Hb, serum albumin, Na, K, Ca, Mg, PO4, pH, HCO3, and WBCs were observed over time.

Conclusion: This study provides a comprehensive overview of post-kidney transplant recipients, highlighting the prevalence of electrolyte abnormalities and their temporal evolution. The findings underscore the need for vigilant monitoring and management of electrolyte imbalances in this population, with implications for postoperative care strategies.

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