•  
  •  
 

Subject Area

Cardiology

Article Type

Original Study

Abstract

Objectives: to evaluate the correlation between both glycosylated haemoglobin (HbA1c), fasting blood glucose (FBG) and coronary artery disease (CAD) severity as measured by SYNTAX score in prediabetic patients undergoing elective percutaneous coronary intervention (PCI). Background: Numerous reports that prediabetes, a minimally aberrant glycometabolism, has an independent relationship with cardiovascular disease (CVD) and that it reflects an escalation in the severity and complexity of CAD. Methods: This study was conducted on 92 prediabetic patients undergoing elective PCI in cardiology department in National Heart Institute (EGYPT) in cooperation with cardiology department of Menoufia university hospitals, during a period time from May 2022 to July 2023. Results: The mean Haemoglobin (Hb) was 13.0 ± 1.7, the mean FBS is 117.8 ± 6.1, while the mean HbA1c was 6.1 ± 0.2. The median (IQR) of the SYNTAX score among the studied patients was 6.5 (0 - 19). 80.4% of patients had low SYNTAX score, 9.8% had intermediate score, while 9.8% had high score. Significant positive correlations were detected between Hb, FBS, HbA1c and syntax score. The median of the score was significantly higher among males, smokers, hypertensive patients, and those with positive family history for CAD. No significant relationship was observed between the score and age. Conclusion: In prediabetes there is a strong positive correlation between Hb, FBS, HbA1c and SYNTAX score with higher scores among males, smokers, and hypertensive patients. There is also a significant relationship between number of affected vessels and HbA1c.

Download

Share

COinS