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Subject Area

Pediatrics

Article Type

Original Study

Abstract

Objectives: To spotlight postictal clinical, imaging and laboratory changes in epileptic children.

Background: Postictal state causes clinical, laboratory and imagings changes in epileptic children.

Methods: Ninety six children were selected in this observational study, 64 were epileptic children distributed equally among two groups of patients, as group 1(observed after 1 hour of seizure attack) and group 2 after 1 week of seizure attack. A control group of 32 patients were included fullfilling special criteria: (had no infection, chronic disease or medications) and well matched as regards age, sex and socioeconomic status. All studied children underwent some imaging studies, clinical and laboratory investigations.

Results: The mean age (8.28±4.06) and (7.77±4.56) years for epileptic (groupI and II respectively) and (8.62 ±3.30) years for control group (III). Clinical changes in group 1 such as; headache (56.3%), confusion (21.9%) autonomic and behavioral changes (65.5%) were significantly more than other two groups. Laboratory changes; for example: WBC (white blood cells) counts (10.58±3.79 *10^3) in group 1 were significantly higher other two groups (7.70±1.73*10^3), (7.07±1.37*10^3) respectively. Similarily; significant changes regarding ammonia, urea, creatininephosphokinase (CPK), cortisol, adrenocorticotropic hormone (ACTH), alaninie transferase (ALT) and serum osmolality with p values respectively (P

Conclusion: Postictal showed significant clinical, laboratory and imaging changes of epileptic children that should be followed up and further work up studies are needed to improve outcome and to predict prognosis.

Erratum

Ahmed T. Mahmoud , Thoria A.Omar , Ibrahim A. Soliman , Basim A. Algazzar

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