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Subject Area

Internal Medicine

Article Type

Original Study

Abstract

Objectives: To assess the role of Inferior vena cava diameter (IVCD) and model for end stage liver Disease (MELD) score for detection of hepatorenal syndrome. Background: IVCD and collapsibility index provides noninvasive intravascular volume status (IVS) assessment, independent of hepatic venous pressure gradient (HVPG) or ascites, with the potential for calculating fluid requirements in cirrhosis. Methods: A cross-sectional study was carried out on 96 patients who attended to Internal Medicine department in Menoufia University hospital from October 2019 to February 2021. Results: there was a significant negative correlation between IVCD and MELD, child-Pugh score, meanwhile there is a significant positive correlation between ICVD and Glomerular Filtration Rate (GFR), albumin, and there is a significant negative correlation between IVCD and MELD, child-Pugh score, meanwhile there is a significant positive correlation between ICVD and GFR, albumin. Using ROC curve for IVCD for predicting HRS, the sensitivity was 73.9% and the sensitivity was 77%. Conclusion: Inferior vena cava diameter and MELD score were an effective method for detection of hepatorenal syndrome. The dynamic IVC size and collapsibility index which is evaluated by ultrasonography (US), has been used to predict FR in critical care medicine for many years, because it is noninvasive, lends a rapid diagnosis, and is inexpensive (2, 3) and the collapsibility index (IVCCI) was calculated using the following formula: (dIVC expiration – dIVC inspiration) / dIVC expiration × 100 =IVCCI, can provide a useful guide for noninvasive IVS assessment in cirrhosis.

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