Role of Lung Ultrasonography in Follow up of Adult Patients with Corona Virus Disease 2019

Authors

Nevine M. Soliman, Department of Anesthesiology‚ Intensive Care and Pain Management, Faculty of Medicine, Menoufia University, Menoufia Egypt
Safaa M. Helal, Department of Anesthesiology‚ Intensive Care and Pain Management, Faculty of Medicine, Menoufia University, Menoufia Egypt
Sabry I. Abdalla, Department of Anesthesiology‚ Intensive Care and Pain Management, Faculty of Medicine, Menoufia University, Menoufia Egypt
Abdelsalam S. Abdelsalam, Department of Anesthesiology‚ Intensive Care and Pain Management, Faculty of Medicine, Menoufia University, Menoufia EgyptFollow
Amal I. Abdelrahman, Department of Anesthesiology‚ Intensive Care and Pain Management, Faculty of Medicine, Menoufia University, Menoufia Egypt

Subject Area

Anesthesiology and Intensive Care

Article Type

Original Study

Abstract

Objectives: To evaluate the role of LUS in the follow up of adult patients with COVID 19 in relation to clinical and laboratory data.

Background: LUS has a well -established role in diagnosis of covid-19 infection, and also has advantages over computed tomography (CT) as there is no risk of patients transfer, spread of infection and radiation exposure.

Methods: In this prospective observational single group study, 116 patients confirmed to have (COVID-19) by polymerase chain reaction (PCR) or CT chest were included. LUS, laboratory data including (lymphocytic count, C-reactive protein (CRP), Interleukin 6 (IL- 6), D dimer, and ferritin level), oxygen saturation, the ratio of partial pressure of oxygen in arterial blood (PaO2) to the fraction of inspiratory oxygen concentration (FiO2) P/F ratio, respiratory rate, mode of oxygen delivery and amount of oxygen were assessed on admission and every 3 days during intensive care unit (ICU) stay. Participants had an LUS exam according to a 12-zone protocol. For each of the 12 zones, a score from 0 to 3 was given depending on the finding: irregular or isolated B-lines (1 point), confluent B-lines (2 points), consolidations or pleural effusion (3 points). The total LUS score was calculated by summing the scores of all 12 zones (range of possible scores: 0 36). Hospital mortality was the primary outcome of this study.

Results: There was a statistically significant association between LUS score of patients and the incidence of mortality as non survivors elicited significantly higher LUS score (all patients had severe disease with LUS score >18) compared to survivors at all-time points, also LUS score was significantly positively correlated with each of CRP, procalcitonin, ferritin, IL6 and D-dimer while was negatively correlated with lymphocytic count on admission and after 3, 6, 9, 12 days. After 15 days, LUS score was significantly positively correlated with CRP but was negatively correlated with ferritin

Conclusion: Bedside LUS has the potential to become a reliable tool for dynamic lung monitoring in intensive care and to play an important role in the absence of CT scans, and the LUS score was well correlated with the laboratory findings.

Recommended Citation

Soliman, Nevine M.; Helal, Safaa M.; Abdalla, Sabry I.; Abdelsalam, Abdelsalam S.; and Abdelrahman, Amal I. (2024) "Role of Lung Ultrasonography in Follow up of Adult Patients with Corona Virus Disease 2019," Menoufia Medical Journal: Vol. 37: Iss. 2, Article 12.
DOI: https://doi.org/10.59204/2314-6788.2919