Validity of Serum Lactate to Albumin Ratio and Shock Index in Pediatric Sepsis

Authors

Athar F. Lasheen, Department of Emergency Medicine, Faculty of medicine, Menoufia University, Shibinelkom, Menoufia, EgyptFollow
Tarek M. Rageh, Department of Surgery, Faculty of medicine, Menoufia University, Shibinelkom, Menoufia, Egypt
Ahmed A. Khattab, Department of Pediatrics, Faculty of medicine, Menoufia University, Shibinelkom, Menoufia, Egypt
Nagwan Y. Saleh, Department of Pediatrics, Faculty of medicine, Menoufia University, Shibinelkom, Menoufia, Egypt
Mustafa F. Ebaid, Department of Emergency Medicine, Faculty of medicine, Menoufia University, Shibinelkom, Menoufia, EgyptFollow

Subject Area

Emergency Medicine

Article Type

Original Study

Abstract

Objective: To assess the role of serum lactate to albumin ratio and shock index in septic and critically ill children in Emergency Department and Pediatric Intensive Care Unit (PICU) of Menoufia University Hospital.

Background: Pediatric sepsis is defined as life-threatening organ dysfunction caused by a dysregulated host response to infection. Serum lactate to albumin ratio (LAR) was suggested to be a promising biomarker of pediatric critical illness.

Materials and Methods: This prospective cohort study was conducted on 90 patients with severe sepsis and septic shock according to the International Pediatric Sepsis Definition Consensus conference and admitted into pediatric department (ward or PICU) of Menoufia University Hospital.

Results: Serum Lactate to albumin ratio on day 0 and 1 and shock index pediatric adjusted (SIPA) were significantly higher in children with severe sepsis or septic shock (p

Conclusion: Serum LAR appeared to be a reliable predictor of pediatric critical illness, Shock Index (SI), may be a good noninvasive tool used as an indicator of mortality in pediatric sepsis and septic shock.

Recommended Citation

Lasheen, Athar F.; Rageh, Tarek M.; Khattab, Ahmed A.; Saleh, Nagwan Y.; and Ebaid, Mustafa F. (2024) "Validity of Serum Lactate to Albumin Ratio and Shock Index in Pediatric Sepsis," Menoufia Medical Journal: Vol. 37: Iss. 2, Article 10.
DOI: https://doi.org/10.59204/2314-6788.2920