Study of Colorectal Carcinoma among Lower GIT Symptoms Patients and History of Cholecystectomy

Authors

Abdelnaser Abdel Atti Gadallah, Internal Medicine, Gastroenterology & Hepatology, Faculty of Medicine, Menoufia University, Shebin Elkom, Menoufia, Egypt
Abdullah Abdelaziz Bahnacy Gomah, Internal Medicine, Gastroenterology & Hepatology, Faculty of Medicine, Menoufia University, Shebin Elkom, Menoufia, Egypt
Abdel Rahman Fathy El-Dekin, Internal Medicine, Gastroenterology & Hepatology, Faculty of Medicine, Menoufia University, Shebin Elkom, Menoufia, EgyptFollow
Amira Hosny Mohamed Hegazy, Clinical Oncology and nuclear medicine, Faculty of medicine- Menoufia University, Shebin Elkom, Menoufia, Egypt

Subject Area

Internal Medicine

Article Type

Original Study

Abstract

Objectives: to evaluate the possibility of Cholecystectomy as a risk factor leading to increased incidence of colorectal cancer (CRC) and Correlation of overall survival in CRC in post cholecystectomy patients.

Background: CRC ranks as the third most common malignancy for men and the second most common malignancy for women worldwide, emerging evidence suggests that cholecystectomy might be associated with the development of CRC.

Methods: This Case control retrospective study had been carried out on two groups: Group A (cases) included 65 patients had CRC which were further divided into 2 subgroups: group A1 included 34 patients with history of cholecystectomy and group A2 included 31 patients with no history of cholecystectomy. Group B (control) included 65 patients without CRC. The data were collected from files from October 2019 to October 2022. All patients were selected from those who were attending the Endoscopy unit of Internal Medicine department of Menoufia University and Clinical Oncology Department, Menoufia University. Data of the patients was gathered from files regarding history taking and clinical examination, investigations and history of cholecystectomy in these patients to detect it as a risk factor.

Results: Cholecystectomy increase the risk for developing colorectal carcinoma but does not affect the overall survival of the patients

Conclusion: Cholecystectomy can be considered as a risk factor for colorectal carcinoma. And there is no difference between the overall survival status in colorectal cancer patients with and without history of cholecystectomy.

Recommended Citation

Gadallah, Abdelnaser Abdel Atti; Gomah, Abdullah Abdelaziz Bahnacy; El-Dekin, Abdel Rahman Fathy; and Hegazy, Amira Hosny Mohamed (2024) "Study of Colorectal Carcinoma among Lower GIT Symptoms Patients and History of Cholecystectomy," Menoufia Medical Journal: Vol. 37: Iss. 1, Article 37.
DOI: https://doi.org/10.59204/2314-6788.1155