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Subject Area

Ophthalmology

Article Type

Original Study

Abstract

Objectives: To evaluate the Histopathological changes in specimens of levator palpaberae superioris muscle of patients with different degrees of congenital Ptosis. Background: Ptosis, also called blepharoptosis, is known as the drooping of the upper eyelid. Simple congenital ptosis is the most prevalent form of congenital ptosis. Levator palpebrae superioris (LPS) and Muller's muscle are two muscles of upper eyelid responsible for its elevation. The levator palpebrae superioris is a triangular-shaped muscle located in each upper eyelid. Subjects and methods: This prospective analysis included a total of 30 eyelids of patients with different degrees of ptosis eligible for the study who underwent levator resection through skin approach then sent for assessment by histopathologist. Patients presented with ptosis were examined and enrolled from March 2022 to June 2023, from the outpatient ophthalmic clinic of Menoufia University Hospital. Results: There was a statically significant difference between the studied cases regarding percentage of muscle fiber components, percentage of fatty tissue components and percentage of fibrosis. The presence of muscle fibres correlates with the degree of ptosis and levator muscle function. The severity of congenital ptosis correlates positively with the degree of histopathological changes of the levator muscle. Conclusion: Examination of all cases with different degrees of congenital ptosis show significant correlation between histopathological findings and grades of ptosis as followings: Increasing of fatty tissues infiltration and fibrosis in sever congenital ptosis more than moderate more than mild ptosis. Presence of muscle fibers in mild ptosis more than moderate more than sever ptosis.

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