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Subject Area

Ophthalmology

Article Type

Original Study

Abstract

Objective This study aimed to assess health-related quality of life (HR-QOL) in children with chronic uveitis. Background Pediatric uveitis is an inflammatory ocular disease that can lead to severe ocular complications. It can significantly affect the HR-QOL of children and daily function. Patients and methods In this case–control study, HR-QOL was evaluated in 20 children with chronic uveitis and 20 children without chronic uveitis. The cases were recruited from the Ophthalmology Department in Menoufia University, and controls were recruited from a school. HR-QOL was evaluated by the Pediatric Quality of Life Inventory Version 4.0 (PedsQL 4.0). Results Uveitis-related data are dependent on full ocular examination by using a slit lamp, fundus examination, visual acuity, and measuring intraocular pressure. Cases had significantly higher scores of three child domains, with P value less than 0.001, whereas there was no significant difference between cases and controls according to the last child domain (emotional functioning), with P value of 0.320. There were no significant differences between the two studied groups according to the parent domains. Conclusion The visual prognosis of a child is severely affected by chronic uveitis, so regular assessment and adequate care can protect visual function. In this study, we found no significant correlation between the presence of uveitis, visual acuity, and quality of life, which was assessed by the PedsQL 4.0. This may be owing to the small size of the sample. Prospective studies on larger samples are needed to confirm these results.

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