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Subject Area

Radiology and Imaging Sciences

Article Type

Original Study

Abstract

Objective To compare cancer detection rates of digital breast tomosynthesis (DBT) plus conventional digital mammography (DM) with those of conventional DM alone. Background DBT is a recent evolution of full-field digital mammography (FFDM) involving quasi-three-dimensional (3D) transformation of breast images. Patients and methods The study was conducted on 35 females who were eligible for examination by 3D DBT, who were referred to the National Cancer Institute – Female Imaging Unit in the duration from May 2020 to May 2021. Full history taking and complete clinical examination were performed on all patients. All patients were examined by FFDM and wide-angle 3D DBT. Results The diagnostic performance of combined DBT + DM outcome, when compared with the results of histopathological assessment of lesions biopsies, was as such: sensitivity (92.6%), specificity (87.5%), positive predictive value (96.2%), negative predictive value (77.8%), and accuracy (91.4%), which indicates statistically significant agreement between the two tests as their yielded weighted κ value is 0.767, which indicates a substantial agreement with a highly significant P value. However, it is only, in case of DM alone, a weighted κ value of 0.449 indicates a moderate agreement with a significant P value. Conclusion DBT showed better detection of subtle spiculations and enhanced ability of multifocality identification due to its ability to overcome tissue overlapping unlike DM alone.

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