Subject Area
Obstetrics and Gynecology
Article Type
Original Study
Abstract
Background Recurrent pregnancy loss (RPL) is defined as the spontaneous loss of two or more clinical pregnancies as documented by ultrasonography or histopathologic examination, which occurs in up to 5% of women in the reproductive age. Objectives To evaluate the relationship between changes in blood indices and RPL. Patients and methods Our case–control study was conducted on 150 women attending Obstetrics and Gynecology Department, Faculty of Medicine, Menoufia University. They were divided into group A (100 women), who had a history of RPL, and group B (50 women), who had given birth at term (>37 weeks of gestation) to healthy infants. Results There were highly significant differences between the two groups regarding platelet distribution width. Receiver operating characteristic curve analysis showed that platelet distribution width could significantly predict repeated pregnancy loss (P < 0.05). Moreover, there were highly significant differences in red blood cell distribution width-standard deviation and red blood cell distribution width-coefficient of variation. Receiver operating characteristic curve analysis showed that red blood cell distribution width-standard deviation and red blood cell distribution width-coefficient of variation could significantly predict repeated pregnancy loss (P < 0.05). Conclusion Platelet indices and red blood cell indices can be used as predictors of RPL as they are of low cost and easily available tests.
Recommended Citation
Abd El-Gayed, Alaa M.; Khattab, Asmaa M.; Salama, Heba F. M.; Anter, Mohamed E.; and Dawood, Ragab M.
(2022)
"Relationship between platelet indices and red blood cell indices and recurrent pregnancy loss,"
Menoufia Medical Journal: Vol. 35:
Iss.
3, Article 78.
DOI: https://doi.org/10.4103/mmj.mmj_68_22
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