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Subject Area

Chest

Article Type

Original Study

Abstract

Objective To investigate the diagnostic accuracy of some screening procedures as predictors of coronavirus disease 2019 (COVID-19) positivity in Egyptian community. Background COVID-19 has been recognized as a pandemic by the WHO. Multiple studies suggest that computed tomography (CT) should be a primary diagnostic tool for COVID-19 because they reported sensitivities with CT far superior to that of reverse-transcriptase (RT) PCR testing. Clinical features varied in different cases, and some patients showed asymptomatic infection. Patients and methods This study is a cross-sectional study, which was conducted on patients who were suspected of novel coronavirus infection attending Mehalla Chest Hospital. Results CT and laboratory were significant screening procedures with sensitivity of 72.8% and specificity of 100%; besides, negative predictive value was 24.2% and positive predictive value was 100% with accuracy of 75% for predicting COVID-19 positivity. Conclusion This is a cross-sectional randomized observational study that was conducted in Mehalla Chest Hospital. This study looks into CT chest imaging, D-dimer, C-reactive protein, and ferritin tests along with PCR, and suggests that if PCR is not an option, other testing methods for COVID-19 are not merely adequate, but could be very useful in rooting out positive cases and could even be used to measure outcome and mortality of COVID-positive patients.

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