•  
  •  
 

Subject Area

Obstetrics and Gynecology

Article Type

Original Study

Abstract

Objective To compare the efficacy, tolerability, and compliance of iron fumarate, iron bisglycinate, and iron polysaccharides for the treatment of iron deficiency anemia during pregnancy. Background Iron deficiency anemia during pregnancy is a significant worldwide health problem. Therefore, routine iron supplementation during the second half of pregnancy has been recommended. Patients and methods A double-blind study was carried out at the Obstetrics Department in Wadi-El Natroun General Hospital on 120 pregnant females with confirmed iron deficiency anemia from August 2019 till August 2020. Study medications were supplied in the form of tablets. Group A: 100 mg of iron fumarate, once daily. Group B: 100 mg of iron bisglycinate, once daily. Group C: 100 mg of iron polysaccharide, once daily. Full history taking and complete clinical examination was done. Hemoglobin (Hb), mean corpuscular volume, and reticulocyte count were assessed at day 0, and then at the end of first, second, and third month. Serum ferritin was assessed at recruitment (day 0) and at the end of 3rd month. Results Our results found that there is high significant difference between the studied groups as regards serum ferritin, Hb and reticulocyte count and serum ferritin (after treatment). However, there was no significant difference regarding mean corpuscular volume. Conclusion Ferrous fumarate achieve a faster cure rate and have better results of mean Hb and serum ferritin level than iron bisglycinate and iron polysaccharide in iron deficiency pregnant women.

Download

Share

COinS