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Subject Area

Obstetrics and Gynecology

Article Type

Original Study

Abstract

Objective To establish whether metoclopramide plays a role in shorting the length of labor. Background The actual role of metoclopramide concerning cervical dilatation to improve labor progress is still controversial. Patients and methods A prospective randomized control study was conducted on 100 pregnant women who were admitted to Etay-Elbaroud Hospital. They were divided into two equal groups; each included 50 pregnant women. Each group received a prefilled syringe with either metoclopramide or saline. Results The results indicated that there were statistically significant differences between the two studied groups regarding cervical dilation at 2, 4, 6, 8, and 10 h, as P values were 0.018, 0.001, more than 0.001, more than 0.001, and 0.043, respectively. Regarding full cervical dilatation, there were statistically significant differences between the two studied groups regarding cervical dilation at 6, 8, and 10 h, as P values were 0.037, 0.001, more than 0.001, and more than 0.001, respectively. Kaplan–Meier survival analysis showed a significant difference in the probability of faster delivery among women who were treated with metoclopramide and others who were treated with placebo (P = 0.036). Conclusion Metoclopramide usage in the first stage of labor significantly enhances cervical dilatation, which subsequently may shorten the duration of labor.

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