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Subject Area

Dermatology

Article Type

Original Study

Abstract

Objectives The objective of the study was to evaluate the effect of sildenafil citrate on sperm motility. Background Phosphodiesterase type 5 inhibitors are now the first line in the treatment of erectile dysfunction. Many men use sildenafil citrate in their reproductive years. This study aimed to study the effect of the drug on sperm motility. Patients and methods This study included a total of 40 patients with erectile dysfunction. Twenty patients received daily 50 mg oral sildenafil citrate for 90 days compared to 20 control patients regarding their sperm motility. Results Cases showed higher sperm motility with a mean 61.2 ± 10.6 than control with a mean 59.8 ± 9.4 but with no significant difference between both groups with P value 0.615. Conclusion This study showed the safety of sildenafil citrate on reproduction with no effect on sperm motility.

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