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Subject Area

Obstetrics and Gynecology

Article Type

Original Study

Abstract

Objectives To assess the role of vaginal misoprostol before intrauterine device (IUD) insertion. Background Misoprostol is an effective method for the treatment of missed and incomplete abortion, induction of provocative abortion as well as for labor induction and prevention and treatment of postpartum hemorrhage. Moreover, several studies have shown the benefit of misoprostol as a cervical ripening agent in nonpregnant women. Patients and methods This is a randomized, clinical trial that included 80 females above the age of 18 years in their fertility period, who want to insert Copper T380 IUD. They were randomly assigned into two equal groups: the first group for vaginal misoprostol and the second group for placebo before IUD insertion. Data were collected and tabulated. Results There was statistically significant difference between the misoprostol group and the placebo group regarding cervical ripening during sound examination and IUD insertion with a P value of 0.000. There was also significant difference in the occurrence of pain with a P value of 0.000 according to visual analog scale. Conclusion Vaginal misoprostol (400 μg) 3 h before IUD insertion in women with past history of cesarean section (no previous vaginal delivery) seems to be associated with higher successful rate of insertion and reduced complications of IUD insertion such as pain and bleeding.

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