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Subject Area

Obstetrics and Gynecology

Article Type

Original Study

Abstract

Objectives To compare initiation of delivery versus expectant management in women with late preterm mild preeclampsia between 34 and 37 weeks of gestation to determine whether planned delivery reduces maternal adverse outcome without substantial worsening of neonatal outcome. Background In women with late preterm preeclampsia (between 34 and 37 weeks of gestation), the optimal time for delivery is less clear, because limitation of maternal disease progression needs to be balanced against complications for the neonate. Patients and methods This prospective comparative randomized controlled study was conducted by an obstetrician in the period of 1 year in Obstetrics and Gynecology Department at Menoufia University Hospital and El-Menshawy General Hospital. It included 92 pregnant women with late preterm mild preeclampsia divided into two groups: 46 for expectant and 46 for termination. Primary and secondary maternal and fetal outcomes were registered and compared for the two groups. Results Of 46 pregnant women managed by termination, three (6.52%) cases only from termination group progressed to severe preeclampsia, whereas 11 (23.91%) cases from the expectant group progressed to severe preeclampsia. There is a statistically significant difference between numbers of cases progressing to severe preeclampsia in both groups (P = 0.020). There is no significant difference in other primary and secondary outcomes. Conclusion Our study showed that the planned early delivery was better for cases with preterm mild preeclampsia between 34 and 37 weeks of gestation.

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