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Subject Area

Obstetrics and Gynecology

Article Type

Original Study

Abstract

Objectives To assess cluster of differentiation 93 (CD93) protein serum level in psoriasis cases and its role in the disease pathogenesis. Background Psoriasis is a common, chronic inflammatory skin disease. It is a complex multifactorial condition related to a combination of genetic, environmental, and immunological factors; hence, this study was established to study the role of CD93 in the psoriasis pathogenesis. Patients and methods This prospective study was carried out during the period from June 2018 to December 2018. This case–control study was conducted on 30 patients with psoriasis vulgaris and 20 age-matched and sex-matched healthy volunteers as a control group. Cases were selected from the Dermatology Outpatient Clinic at Menoufia University Hospital during the period from June 2018 to December 2018. Control were selected from the healthy staff of Menoufia University Hospital. The laboratory part of the study was done at the Biochemistry Department of Menoufia Faculty of Medicine. Results There were no significant differences in CD93 protein levels in serum between patients with psoriasis and controls. Conclusion There were no differences in CD93 protein expression in serum among psoriasis cases and control group.

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