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Subject Area

Obstetrics and Gynecology

Article Type

Original Study

Abstract

Objective The objective of this study was to evaluate serum visceral adipose tissue-derived serpin (vaspin) level with the severity of coronary artery disease (CAD). Background There is controversy between the researchers on the subject of serum vaspin concentration in CAD. Patients and methods Twenty control and 68 CAD patients were enrolled in this study. Vaspin was detected by enzyme-linked immunosorbent assay method. Results Serum levels of vaspin were significantly low in patients with CAD compared with healthy controls and low vaspin concentrations were correlated with CAD severity. Conclusions Decreased serum vaspin levels were observed in the existence and severity of CAD in patients assessed by coronary angiography.

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