•  
  •  
 

Subject Area

Otorhinolaryngology

Article Type

Original Study

Abstract

Objective To determine the seroprevalence of hepatitis A virus (HAV) and hepatitis E virus (HEV) among the patients admitted to a hospital on presenting the symptoms of acute viral hepatitis. Background HAV and HEV are enterically transmitted viruses responsible for causing acute viral hepatitis. They pose a heavy burden on the health care system of developing nations. Patients and methods A hospital-based study was conducted for a period of 18 months from September 2019 to February 2020. A total of 170 patients were considered for the study. Overall, 3–5 ml of venous blood samples was collected from patients presenting with the symptoms of acute viral hepatitis. Their serum was subjected to enzyme-linked immunosorbent assay test (DiaPro Diagnostic Bioprobes) for detection of anti-HAV and anti-HEV immunoglobulin M. Results Of the 170 serum samples tested, 35.8% samples were found to be positive for HAV and 51.7% samples were positive for HEV. Male preponderance was detected during both the infections. HAV was more common in pediatric population, whereas HEV was common among adult population. Coinfection was found to be 1.7%. Conclusion Our study mandates the screening of these enteric viruses so as to prevent the further complications associated with the disease. The data collected would essentially help in planning the vaccination strategies along with sanitation and hygiene in our geographical region.

Download

Share

COinS