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Subject Area

Ophthalmology

Article Type

Original Study

Abstract

Objective The aim was to evaluate echocardiographic changes and cardiovascular (CV) risk in psoriatic patients in comparison with controls. Background Psoriasis is a chronic autoimmune inflammatory skin disorder. Its incidence rate is 2.8%. Psoriasis is associated with numerous comorbid diseases, including cardiometabolic, gastrointestinal, and kidney diseases as well as malignancies, infections, and mood disorders. CV diseases are of particular importance, as they often directly affect the patients' mortality. Psoriasis is associated with CV risk factors such as hypertension, diabetes mellitus, dyslipidemia, obesity, and metabolic syndrome. Patients and methods This case–control study was carried out on 45 cases with psoriasis and 39 age-matched and sex-matched healthy participants as a control group. All participants were subjected to full history taking, general examination, local examination with determination of site of lesions and assessment of Psoriasis Area and Severity Index score, and echocardiography. Results Our results showed that there was a significant difference between cases and controls regarding ECHO cardiographic results, with 60% of cases having abnormal ECHO finding (pulmonary hypertension was present in 10% of cases, ischemic heart disease was present in 10% of cases, whereas valvular heart disease was present in 40% of cases), and no abnormal finding among control group. Conclusion Echocardiographic abnormalities could be found in psoriasis compared with normal population. Psoriasis, may be an independent CV risk factor. Psoriasis is more commonly associated with valvular heart disease but less commonly with pulmonary hypertension or ischemic heart disease.

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