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Subject Area

Otorhinolaryngology

Article Type

Original Study

Abstract

Objective The aim of this work is to evaluate lipid profile in patients with androgenetic alopecia and to correlate their levels with disease severity. Background Androgenetic alopecia (AGA) is the most common form of alopecia which is an androgen hormone-dependent process with continuous miniaturization of hair follicles in both genetically predisposed men and women. Lipids are a broad group of naturally occurring molecules. AGA has been found to be associated with coronary artery disease (CAD). The well-known risk factors of CAD are family history of CAD, hypertension, increased BMI, central obesity, hyperglycemia, and dyslipidemia. Patients and methods This case–control study was carried out on 30 men with early-onset AGA and 30 age-matched and sex-matched healthy subjects as the control group. All patients were subjected to full history taking, general examination, and laboratory investigations (fasting blood sugar and blood lipid profile). Results Our results showed no significant difference between cases and controls regarding age and sex. There were statistically significant differences regarding mean values of body weight, waist circumference, and BMI between cases and controls. There were statistically significant differences regarding mean values of fasting blood sugar, triglycerides, high-density lipoprotein cholesterol, low-density lipoprotein cholesterol between cases and controls. Conclusion Patients with AGA appear to be at an increased risk of developing CAD and high blood lipids.

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