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Subject Area

Clinical Laboratory

Article Type

Original Study

Abstract

Objective This study aimed at evaluating the effect of using a combination of platelet-rich plasma (PRP) and hyaluronic acid (HA) 3.5% using microneedling in facial skin rejuvenation and to estimate the visible skin improvement and patient satisfaction. Background PRP has attracted attention in the field of dermatology, specifically in the aesthetic field for skin rejuvenation. HA is involved in maintaining skin hydration. PRP along with HA offers a good combination for skin rejuvenation via microneedling for augmentation of collagen content, for increasing moisture, and for offering a rich source of growth factors. Materials and methods A total of 30 participants were enrolled in study and received facial treatments with PRP and HA through microneedling using dermapen every 2 weeks, and the results were evaluated through the assumed visual assessment scale. Results The results yielded statistically significant improvement concerning skin texture, dullness, acne, acne scars, wrinkles, wide pores, pallor, and firmness compared with baseline. Moreover, enrolled participants showed marked satisfaction with the results with minimal adverse effects. Conclusion PRP along with HA represents a potentially effective and safe material for skin rejuvenation through microneedling using dermapen.

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