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Subject Area

Endemic and Tropical Medicine

Article Type

Original Study

Abstract

Objectives To compare transvaginal measurement of cervical length and insulin-like growth factor-binding protein-1 (IGFBP-1) in the prediction of successful induction of labor. Background The successful induction of labor aims to achieve vaginal delivery when the continuation of pregnancy presents a threat to the life or well-being of the mother and fetus. The process of induction should only be considered when vaginal delivery is felt to be the appropriate route of delivery. Patients and methods A total of 140 women, 37–42 weeks in pregnancy, underwent induction of labor. Before induction, detection of IGFBP-1 in cervical secretions by the Actim partus test was done, then a digital examination of the cervix was performed, and the Bishop score was noted. Cervical length was measured by transvaginal ultrasound. Results The mean cervical length in patients delivered vaginally was 24.89 ± 5.48 mm whereas the mean cervical length in patients delivered by cesarean section was 26.79 ± 3.06 mm. IGFBP-1 is positive by Actim partus test in 94% in patients delivered vaginally, whereas IGFBP-1 is positive by Actim partus test in 39.5% in patients delivered by cesarean section. Conclusion There was a statistically significant positive correlation between detection of IGFBP-1 in cervical secretions and successful induction of labor.

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