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Subject Area

Clinical Pathology

Article Type

Original Study

Abstract

Objective The aim was to compare the choroid thickness (CT) in eyes with newly discovered glaucoma with the eyes of healthy controls. Background Glaucoma is characterized by progressive damage to retinal ganglion cells, leading to optic nerve head morphological changes, thinning of the retinal nerve fiber layer (RNFL), and loss of visual field. Materials and methods A total of 100 patients (100 eyes) with newly discovered glaucoma and 50 age-matched normal participants underwent macular CT scanning using enhanced-depth imaging-optical coherence tomography (EDI-OCT). The average subfoveal choroid thickness (SFCT) of the glaucoma eyes was compared with that of normal eyes. Results The CT, RNFL, and intraocular pressure (IOP) were found to have significant changes between glaucomatous and normal eyes. The mean CT under the fovea (SFCT) was 277.3 ± 37.78 μm in the glaucomatous eyes, which was found to be thicker than in normal eyes (259.8 ± 24.92 μm) (P < 0.05). Mean RNFL was thinner in glaucomatous eyes (91.39 ± 12.47) than in normal eyes (110.9 ± 7.40) (P < 0.05). Mean IOP was 26.16 ± 3.0 in glaucomatous eyes and 19.50 ± 2.59 in normal eyes. The correlation between IOP and both RNFL and CT was not significant, with P = 0.825 and 0.230, respectively. Conclusion The CT is higher in patients with glaucoma than in normal group based on EDI-OCT measurements.

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