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Subject Area

Cardiology and Vascular Medicine

Article Type

Original Study

Abstract

Objective The aim was to determine the changes in the ocular high-order aberrations (HOAs) after corneal cross-linking (CXL) in patients with keratoconus and its correlation with the changes in visual acuity (VA). Background HOAs are among the important refractive and visual quality properties of the human ocular system, and the decreased levels of some visual features such as contrast sensitivity have been partially attributed to these parameters. Evaluation of long-term changes of HOAs after CXL is useful in understanding the efficacy of CXL on improving optical, refractive, and VA. Patients and methods All patients were subjected to preoperative and postoperative assessment for best-corrected VA, anterior segment examination (cornea, iris, and lens), posterior segment examination (vitreous and retina), corneal topography, and HOA using Oculus Pentacam II. Results Regarding coma and trefoil aberrations, there was a statistically insignificant difference preoperatively and postoperatively in both eyes, as P value was more than 0.05. The total HOAs were statistically significant preoperatively and postoperatively, as P value was less than 0.05. Conclusion Total HOAs and keratometric readings significantly decreased after CXL. Ocular aberrations play a key role in influencing retinal image quality. Correcting HOAs in patients with keratoconus is likely to improve the quality of vision significantly.

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