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Subject Area

Dermatology

Article Type

Original Study

Abstract

Objectives The objective of this study was to evaluate the effect of local ozone as an adjuvant therapy in patients with diabetic foot ulcers. Background Diabetes mellitus is a major problem that results in complications such as infections, gangrene, amputation, coma, and death. Diabetic foot ulcer can be treated by many methods; recently, ozone has been used in their treatment. Patients and methods A prospective cross-sectional study was conducted at Menoufia University Hospital and Moustafa Kamel Military Hospital for the treatment of foot ulcer. Sixty patients were selected on clinical, laboratory, and radiological bases. They were divided into 39 patients who had complete healing, 13 patients who had partial healing, and eight patients had no healing. All patients received two sets of local ozone therapy weekly for 10 weeks. They were evaluated for degree of healing and followed-up for 8 weeks after the end of therapy for healing. Results There were no significant differences between the studied groups with regard to age, sex, and type of diabetes. There was a significant reduction in the length of treatment and size of the ulcer in the healing group. Most of our patients showed complete healing (65%) and 21.6% showed partial healing, while only 13.4% showed nonhealing. Only 11.4% of cases of complete healing recurred. Conclusion The use of local ozone therapy markedly improves healing of diabetic foot ulcers with low incidence of recurrence.

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