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Subject Area

Dermatology

Article Type

Original Study

Abstract

Objective The objective of the study was to determine the value of white cell count (WBC), C-reactive protein (CRP), and bilirubin as diagnostic markers in acute appendicitis. Background Appendicitis is a frequent reason for hospital admissions. Elevated CRP, white blood cell count, and serum bilirubin have been suggested as individual markers for appendicitis and appendicular perforation. Patients and methods This prospective observational study was conducted on patients admitted with clinical suspicion of acute appendicitis at Menoufia University and Bolak El-Dakror Hospitals in the 6 months period starting from June 2017 involving 150 patients. Results A total of 150 patients were operated under suspicion of appendicitis. From these, 65.3% of patients had simple appendicitis, 18.7% had normal appendix, and 16% of patients had complicated appendicitis. Complicated appendicitis was accompanied with higher WBC level with significant correlation (P = 0.03); complicated and simple ones were accompanied with a higher level of total bilirubin than normal appendix with significant differences (P < 0.001). Complicated appendicitis and simple appendicitis were accompanied with higher CRP positivity than in normal appendix with significant differences (P < 0.001). Conclusion Combining blood markers was useful in predicting appendicitis and perforated appendicitis, in addition to CRP and WBC, and blood levels of bilirubin.

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