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Subject Area

Pediatric Surgery

Article Type

Original Study

Abstract

Objective To evaluate the accuracy of change in leukocytes count in comparison with clinical pictures and histopathology in diagnosis of acute appendicitis. Background The diagnosis of acute appendicitis is primarily clinical and should be made on clinical symptoms and signs. However, some patients have equivocal physical findings and may be admitted for a period of observation. We suggest that these patients could also have serial total white cell counts taken as an aid for diagnosis. Patients and methods The study is a prospective randomized clinical trial. This study was conducted on patients presenting to the General Surgery Department in Menoufia University Hospitals and Al Minshawy General Hospital in Tanta during the period from March 2017 to March 2018. This study included 68 patients with acute lower abdominal pain suspecting acute appendicitis divided into two groups: A (34 patients) and B (34 patients). Patients in group A had normal leukocytes count and patients in group B had a high leukocyte count. All specimens of appendectomies were sent for histopathological examination. Results The leukocytes count has a sensitivity of 58%, specificity of 85%, accuracy of 63%, and negative appendectomy rate of 19%. Conclusion It was found that if the total leukocytes count and neutrophils were highly elevated and correlated with the clinical picture, the diagnostic accuracy of acute appendicitis was more increased.

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