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Subject Area

Dermatology

Article Type

Original Study

Abstract

Objective The aim was to evaluate breast lesions using mammography (MG) and ultrasonography (USG) independently and in combination in women with dense breasts. Background Women with dense breasts are at higher risk of developing breast cancer and at greater risk of cancer being not detected because of masking of the radiological signs of cancer by increased density. Therefore, multiple imaging modalities are required. USG is an imaging modality that can overcome limitations of MG and it is important for correct diagnosis. Materials and methods Our study was carried out on 100 female patients with dense breast lesions who attended Menouf General Hospital from October 2015 to March 2017. All of them were examined clinically followed by both MG and USG examinations. Then, we compared the findings with pathology results to assess their diagnostic performance. Results Of all 100 patients included in this study, the benign lesions were 60, whereas the malignant lesions were 40. Considering, MG had a sensitivity of 40%, a specificity of 93%, a positive predictive value (PPV) of 80%, and a negative predictive value (NPV) of 70%, and ultrasound had a sensitivity of 90%, a specificity of 100%, a PPV of 100%, and a NPV of 94%, and the indices of combined MG with ultrasound revealed sensitivity of 100%, specificity of 93%, PPV of 91%, and NPV of 100%. Conclusion USG should be considered as an important screening and diagnostic adjunct to MG to minimize the chances of missing diagnosis of any dense breast lesions.

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