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Subject Area

Obstetrics and Gynecology

Article Type

Original Study

Abstract

Objective The aim of this review was to perform a systematic review to highlight thromboembolic diseases and current strategies to manage and prevent it. Data sources Data were obtained from Medline databases (PubMed, Medscape, and Science Direct) and all materials available on the internet from the start data of each database to 2017. Study selection The selected articles are systematic reviews and experimental studies that address the management of thromboembolic diseases. Data extraction Extraction was performed according to the validity, quality, and originality of the selected reviews and studies that fulfilled the previous criteria; in addition, the focus was on studies that present the latest or the most updated findings on application of management of thromboembolism. Data synthesis Each review and study was examined. The layout was selected to present wide range of data including the most recent findings on this participants. Significant data were collected, thus a structured review was performed. Conclusion We found that thromboprophylaxis is recommended. Low-molecular-weight heparin could be more effective than unfractionated heparin for thromboprophylaxis. Vitamin K antagonists need regular monitoring to avoid both thrombotic and bleeding complications, whereas NOACs do not require laboratory monitoring. Results In total 12 potentially relevant publications were included: six discussed management of thromboembolism and six discussed new oral anticoagulants (NOACs). NOACs can be viewed as an alternative to standard treatment.

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