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Subject Area

Tropical Medicine

Article Type

Original Study

Abstract

Objectives The objective of this study was to estimate the correlation between diabetes mellitus (DM) and arthritis through some laboratory changes in patients with type 2 DM complaining of arthropathy. Patients were recruited from outpatient clinics of Internal Medicine Department at Menoufia University Hospital. Background DM has become one of the main threats to human health in recent decades. Uncontrolled diabetes is strongly correlated to causing long-term microvascular and macrovascular complications. Rheumatological diseases are now common, which have an increased prevalence in the diabetic population. Patients and methods The study included 90 patients. Patients were divided into three groups: group 1 comprised 30 patients with type 2 DM without arthropathy, group 2 comprised 30 patients with type 2 DM with arthropathy, and group 3 comprised 30 nondiabetic patients with arthropathy. Results BMI was significantly higher among patients with arthropathy (33.64 ± 2.26), random blood sugar was significantly higher among patients with arthropathy (288.10 ± 83.64), Alc was significantly higher among patients with arthropathy (8.72 ± 1.09), erythrocyte sedimentation rate was significantly higher among nondiabetic patients (58.60 ± 27.29), serum uric acid was significantly higher among nondiabetic patients (5.11 ± 1.18), C-reactive protein was higher among diabetic patients with arthropathy (60%), rheumatoid factor was significantly higher among patients with arthropathy (75.0%), and antinuclear antibody was significantly higher among patients with arthropathy (98.0%). Conclusion Musculoskeletal complications were most commonly seen in patients with a long-standing history of type 2 DM. The incidence of DM and the life expectancy of the diabetic patient have both increased, resulting in increased prevalence and clinical importance of musculoskeletal alterations in diabetic patients. The development of musculoskeletal disorders is dependent on age and the duration of DM.

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