•  
  •  
 

Subject Area

Tropical Medicine

Article Type

Original Study

Abstract

Objectives The objective of this article is to analyze the changes in the retinal nerve fiber layer (RNFL) thickness in retinal vein occlusion using optical coherence tomography. Background Optical coherence tomography is a noninvasive test that gives high-resolution sectional images of the RNFL that are used to measure RNFL thickness in studies of glaucoma and other optic neuropathies. Patients and methods The study included 50 eyes (25 right and 25 left eyes) of 25 adult patients having unilateral branch retinal vein occlusion, for which optical coherence tomography was obtained. Results There was a statistical significant difference between normal and diseased eyes regarding retinal nerve fiber thickness (P < 0.001). The RNFL thickness is significantly lower in patient with history of diabetes mellitus than those with no history (P = 0.0321). The mean RNFL thickness was 50.10 ± 25.23 μm for diabetic patients. The nerve fiber layer thickness is significantly lower in patients with hypertension than in those with no history (P = 0.002). The mean nerve fiber layer thickness was 44.38 ± 23.2 μm for patients with hypertension. The thickness is significantly lower in patient with history of glaucoma than those with no history (P = 0.002). The mean nerve fiber layer thickness was 40.42 ± 23.15 μm for patients with glaucoma. Conclusion Optical coherence tomography might reflect the thinning of the RNFL after branch vein occlusion and showed that RNFL damage had a relationship with other ocular and systemic diseases.

Download

Share

COinS