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Subject Area

Radio diagnosis

Article Type

Original Study

Abstract

Objective The aim of this st udy is to investigate the relation between glycemic control in first half of pregnancy by measuring mid-pregnancy glycated hemoglobin (HbA1c), neonatal birth weight, and amniotic fluid volume. Background Glycosylated hemoglobin is an important method for assessing glycemic control showing both fasting and postpradial plasma glucose levels. Patients and methods A prospective observational study was conducted on 150 pregnant women attending the Obstetrics and Gynecology Outpatient Clinic at Tala General Hospital from January 2015 to December 2016. Detailed history and general, abdominal, and sonographic examination were analyzed for all patients. Results A statistical difference between normal birth weight (NBW) and macrosomia regarding obstructed and preterm labor up to 36 weeks was recorded, which was higher in macrosomic group, whereas a highly significant difference regarding perineal tear, Neonatal Intensive Care Unit admission, hypoglycemia, and hyperbilirubinemia occurred in 11, 17, eight, and 21 cases of NBW group, and occurred in three, five, and four cases of macrosomic group, respectively. Moreover, HbA1c was positively correlated with BMI, amniotic fluid index (AFI), expected fetal weight (EFW) at 36 weeks of gestation, gestational age at delivery (GA), and diabetic history family, whereas, AFI was positively correlated with body weight. Conclusion HbA1c was positively correlated with BMI, AFI, EFW, GA, and family history of diabetes, and birth weight with AFI and EFW. In addition, highly statistical significantly difference between macrosomic and NBW groups was seen regarding GA, AFI, EFW, and cesarean birth, which were high in macrosomic group.

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