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Subject Area

Obstetrics and Gynecology

Article Type

Original Study

Abstract

Objective The aim of this study was to evaluate choroidal thickness (CT) in patients with diabetic retinopathy (DR) and normal individuals. Data sources Data were collected from Medline databases (PubMed, Medscape, Science Direct, and EMF-Portal) and all materials available in the Internet from 2004 to 2015. Study selection The initial search presented 27 articles, of which five met the inclusion criteria. The articles studied the changes in the mean subfoveal choroidal thickness (SFCT) in different stages of DR. Data extraction If the studies did not fulfill the inclusion criteria, they were excluded. Study quality assessment included whether ethical approval was gained, eligibility criteria specified, appropriate controls, adequate information, and defined assessment measures. Data synthesis Comparisons were made using structured review with the results tabulated. Findings In total, five potentially relevant publications were included; three studies detected a significant decrease in SFCT with progression of DR. Some authors found a correlation between the presence of diabetic macular edema (DME) and changes in choroidal thickness. Three studies detected a significant decrease in SFCT in DME. Conclusion CT is altered in diabetes and may be related to the severity of retinopathy. The presence of DME is associated with a significant decrease in the CT.

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