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Article Type

Original Study

Abstract

Objectives The purpose of this study was to assess the safety and efficacy of multispot laser and conventional laser in the treatment of nonproliferative diabetic retinopathy with clinically significant macular oedema (CSME) in relation to the visual outcome, central macular thickness (CMT) using optical coherence tomography, and presence of adverse events. Patients and methods This prospective randomized study included a total of 50 eyes from the research institute of ophthalmology in 2015 that were divided into two groups of 25 patients each. Group A patients underwent focal or modified grid macular laser photocoagulation using green laser 532 nm. Group B patients underwent focal or modified grid macular laser photocoagulation using multispot laser photocoagulation Valon TT. Inclusion criteria were as follows: type II diabetes and clinically significant macular edema. Best-corrected visual acuity (BCVA), optical coherence tomography readings, intraocular pressure (IOP), and adverse events were recorded preoperatively and at 1 week, 1 month, and 3 months postoperatively. Results The mean preoperative BCVA in conventional laser was 0.294 ± 0.17 decimal and that in multispot laser was 0.30 ± 0.21. The mean BCVA 3 months after laser in group A was 0.4820 ± 0.244 decimal (P = 0.001) and that in group B was 0.50 ± 0.20 (P = 0.001). The mean preoperative CMT in group A was 375.92 ± 65.69 μm and that in group B was 361.0 ± 50.400 μm. The mean CMT 3 months after laser in group A was 314.44 ± 85.94 μm (P = 0.001) um and that in group B was 0322.67 ± 57.50 μm (P = 0.001). The multispot system parameters used a higher power of 155 ± 90.1 mW (P = 0.001) compared with the conventional laser to produce the same therapeutic visible effect. Conclusion Multispot system was safe, rapid, and effective in the treatment of clinically significant macular edema in short-term follow-up periods and had a short exposure time. Although the short pulse duration of the multispot system necessitated the use of a higher power, it was not associated with adverse effects.

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