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Abstract

Design This was a prospective, double-blinded, randomized controlled study. Patients and methods The present study included 100 patients randomized into two groups: group I included patients who did not receive tranexamic acid and group II included patients who were given tranexamic acid after induction intravenously as 15 mg/kg over 10 min. Results In group I, the mean number and weight of gauze used during surgery were 5.1 + 1.30 pieces and 72 ± 6.334 ml, respectively, and in group II, they were 1.9 ± 0.35 pieces and 41 ± 8.221 ml, respectively (P < 0.001). In group I, the mean amount of blood in suction bag was 200 ± 52.36 ml, whereas it was 50 ± 10.36 ml in group II (P < 0.001). The difference between both groups regarding the number of gauze, weight, and the amount of blood in suction bag was highly significant (P < 0.001). Conclusion The present study showed that 15 mg/kg of tranexamic acid can reduce intraoperative blood loss in a highly significant manner in children undergoing tonsillectomy and in keeping stability in hemoglobin, hematocrit levels, heart rate, mean arterial blood pressure, and respiratory rate postoperatively.

Article Type

Original Study

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