•  
  •  
 

Article Type

Original Study

Abstract

Objectives To evaluate the subfoveal choroidal thickness (ChT) in type II diabetes mellitus (DM) using enhanced depth imaging optical coherence tomography (EDI-OCT). Background Diabetic retinopathy (DR) is because of hemodynamic abnormalities. The choroid provides oxygen and nutrients to the outer retina. EDI-OCT can image the choroid in vivo. Patients and methods A prospective clinical randomized study was carried out focusing on 100 eyes of 100 patients divided into two groups: group A included 50 eyes of 50 diabetic patients with type II DM (20–50 years) and group B included 50 eyes of 50 age-matched normal healthy controls with no sex or laterality specification. The subfoveal ChT, using EDI-OCT, was measured from the posterior edge of retinal pigment epithelium to the choroioscleral junction. Results The mean age of the patients was 42 ± 7 and 39 ± 9 years in group A and B, respectively. The mean DM duration in group A was 7.96 ± 3.9 years. Subfoveal ChT was found to be 291 ± 42 μm in group A [275.31 ± 31 μm for no apparent retinopathy (no DR), 298 ± 42 μm for nonproliferative diabetic retinopathy, 309 ± 58 μm for proliferative diabetic retinopathy, 277 ± 29 μm for diabetic macular edema (DME) absent, and 306 ± 47 μm for DME present], whereas it was 284 ± 54 μm in group B. There was a statistically significant positive correlation between subfoveal ChT and DM duration (P = 0.00). Conclusion Subfoveal ChT was found to be correlated with the stage of DR. Progressive thickening of the choroid with the progression of DR and/or the development of DME may reflect the concurrent progression of diabetic choroidopathy.

Download

Share

COinS