A study on the effect of estrogen, progesterone, and their cutaneous receptors in the pathogenesis of melisma

Authors

Mai M. Farag, Menoufia UniversityFollow
Mohamed A. Basha, Menoufia University
Rania M. Azmy, Menoufia University

Article Type

Original Study

Abstract

Objective: The aim of the study was to assess the efficacy of estrogen, progesterone, and their cutaneous receptors in the pathogenesis of melasma. Materials and methods: From January 2013 to June 2013, 40 female patients with melasma and 20 age-matched and sex-matched healthy individuals as the control group were included. Estrogen and progesterone were measured using IMMULITE 2000. Results: Concerning the serum estrogen and progesterone levels, the patients showed a statistically significant increase in progesterone levels with a mean value of 3.65 ± 13.11 when compared with the controls with a mean value of 3.63 ± 2.64. Conclusion: Increase in serum progesterone supports the role of pregnancy in melasma.

Recommended Citation

Farag, Mai M.; Basha, Mohamed A.; and Azmy, Rania M. (2016) "A study on the effect of estrogen, progesterone, and their cutaneous receptors in the pathogenesis of melisma," Menoufia Medical Journal: Vol. 29: Iss. 2, Article 33.
DOI: https://doi.org/10.4103/1110-2098.192411