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Article Type

Original Study

Abstract

Objectives This work aimed to detect the level of free testosterone (FT) hormone in type II diabetic men. Background Testosterone is a cholesterol-based steroid hormone that plays a critical role in numerous biological functions throughout the male life cycle. Diabetes mellitus type 2 is a metabolic disorder that is characterized by high blood glucose in the context of insulin resistance and relative insulin deficiency. Low serum testosterone is associated with a variety of comorbidities, including insulin resistance, type 2 diabetes, obesity, and metabolic syndrome. Materials and methods This study was carried out on 50 diabetic men aged from 25 to 65 years and 20 apparently healthy men, who attended the outpatient clinic of Dermatology, Andrology, and Sexually transmitted diseases. Results The lower levels of FT were found in older diabetic persons; diabetic men were markedly obese and showed higher BMI. They showed low International Index of Erectile Function scores, but higher scores were observed in young patients. The lowest FT levels were found in patients with the highest random blood sugar levels. Conclusion FT levels decrease as a man ages and if he is obese, his testosterone levels decrease even more. Diabetes accentuates these effects. Low testosterone level is a biomarker for diabetes development and high BMI is also highly predictive for development of diabetes.

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