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Article Type

Original Study

Abstract

Objective The aim of this work was to study the pattern of risk factors in patients admitted with acute coronary syndrome (ACS) to the coronary care unit in Menoufia Governorate and their relationship with the in-hospital complications. Background Coronary artery disease is a progressive disease process that generally begins in childhood and manifests clinically in mid-to-late adulthood. Patients and methods The study included 120 patients admitted to Coronary Care Unit with ACS during the period from October 2009 to April 2010. Patients were divided into three groups according to their age (≤40, 40-60, and ≥60 years) and followed up during the period of their admission, and the in-hospital complications were recorded. Statistical presentation and analysis of the present study was conducted using the mean, SD, and the c2 -test by SPSS v. 16. Results Our study included 95 men (79.1%) and 25 women (20.9%). ACS was higher in the older women group III than in the other groups (P < 0.05). Family history and smoking were prevalent in the younger patients group I than in other groups; fasting and 2-h postprandial patients were higher in group II than in other groups; and waist circumference and BMI were significantly higher in group II than in other groups. Women had a higher incidence of diabetes mellitus and hypertension, and more atherogenic lipid profile pattern than men. In contrast, smoking was more prevalent in men (63.1%) than in women (0%). Conclusion Group I (<40 years) had fewer risk factors as they represented the lowest incidence of diabetes mellitus, hypertension, obesity, and metabolic syndrome. In addition, they had better pattern of lipid profile than the other groups. In contrast, they had increased incidence of other risk factors such as positive family history of premature coronary artery disease, higher incidence of current smoking, low HDL value, and being male sex.

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