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Subject Area

Ophthalmology

Article Type

Original Study

Abstract

Objective To compare difluprednate 0.5 mg (0.05%) versus prednisolone acetate 10 mg MedCalc Software (1%) after cataract procedures in diabetic patients regarding their safety and efficacy in postoperative inflammation. Background Cataract is the world's most prevalent cause of vision loss, affecting mostly the elderly. Cataract surgery is now the sole therapy option. As a result, around eight million cataract operations are conducted each year. Furthermore, the higher life expectancy supports the likelihood of even more procedures in the coming years. Patients and methods This prospective interventional comparative research included 74 eyes of diabetic patients with cataract, attending Menoufia University Hospital outpatient clinic, undergoing uncomplicated phacoemulsification. They were divided into two equal groups, each one included 37 patients. The trial duration was from 6 to 12 months. Results Both difluprednate and prednisolone groups showed similar improvements in corneal edema (29.7 vs. 29.7%, respectively), with no substantial variations in the two treatment groups (P = 0.493). Conclusions According to the findings of this research, difluprednate seems to be equally safe and efficacious as prednisolone acetate in managing postoperative inflammation and pain in patients having phacoemulsification.

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