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Subject Area

Radiology and Imaging Sciences

Article Type

Original Study

Abstract

Background Bladder cancer is one of the most common cancers in Egypt. Currently, diffusion-weighted imaging (DWI) is the only imaging technique that is able to assess molecular diffusion in vivo and provide information about the biophysical properties of tissue such as cell organization, density, and microstructure. Objectives This study is designed to detect the value of diffusion-weighted MRI in the diagnosis and staging of urinary bladder cancer. Patients and methods This study is a prospective study of descriptive and analytical design. The study included 30 adult patients with suspected bladder mass, who attended Menoufia University Hospitals. Results This study included 30 adult patients. Regarding histopathological type results, urothelial tumors were found in 25 (83.3%) patients, squamous cell carcinoma was found in four (13.3%) patients, and adenocarcinoma was found in one (3.3%) patient. According to the staging of urinary bladder lesions in diffusion-weighted MRI among the studied patients, DWI showed restricted diffusion in all cases with a low apparent diffusion coefficient value. T staging by DWI showed 56.7% of the patients were of T3 and 6.7% were of T1. Conclusion Adding DWI and the apparent diffusion coefficient value to T2WI improves the accuracy of MRI in bladder cancer detection and staging. This noninvasive method could be efficiently used for the evaluation of patients with hematuria of lower urinary tract origin.

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