Correlation between metabolic syndrome and benign prostatic hyperplasia

Authors

Abd Allah M. Attia, Menoufia University
Haitham M. AbdElaal, Menoufia UniversityFollow
Hossam A. Yasien, Menoufia University
Mohamed S.M. Elgharbawy, Menoufia University

Subject Area

Anesthesiology and Intensive Care

Article Type

Original Study

Abstract

Objective To study the relation between metabolic syndrome (MetS) and benign prostatic hyperplasia (BPH). Background BPH is the most common urological condition among elderly males, with multiple etiopathogenesis. Patients and methods This prospective study was carried out on 90 male individuals aged 45–60 years classified into three groups: group 1 included 30 normal male individuals who had neither MetS nor BPH, group 2 included 30 patients with diagnosed BPH, and group 3 included 30 patients with diagnosed criteria of MetS. Results The study showed that compared with the control group, MetS group has significant higher manifestations of BPH with its different parameters, such as International Prostate Symptom Score (9.47 ± 5.68 vs. 2.87 ± 1.81, P > 0.001), prostate-specific antigen (3.06 ± 2.19 vs. 1.25 ± 0.82, P > 0.001), and prostatic weight (65.3 ± 30.7 vs. 28.7 ± 7.43 P > 0.001). Conclusion This study confirmed the frequent coexistence of MetS and BPH. This association seems to be a consequence of MetS-related changes in the sex hormone milieu and metabolic derangements.

Recommended Citation

Attia, Abd Allah M.; AbdElaal, Haitham M.; Yasien, Hossam A.; and Elgharbawy, Mohamed S.M. (2021) "Correlation between metabolic syndrome and benign prostatic hyperplasia," Menoufia Medical Journal: Vol. 34: Iss. 1, Article 9.
DOI: https://doi.org/10.4103/mmj.mmj_166_19