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Subject Area

Family Medicine

Article Type

Original Study

Abstract

Objective To study the role of diffusion-weighted (DW) imaging in the evaluation of cholangiocarcinoma (CC). Background In analyzing the presentation of different types of CC, DW-MRI as a noninvasive, safe technique had great importance. Patients and methods The patients were referred from Hepatobiliary Surgery and Hepatology Departments of the National Liver Institute, Menoufia University, during the period from October 2016 to November 2018. The study included 50 cases, comprising 34 males and 16 females, with age ranging from 34 to 77 years. Patients who were diagnosed with CC by pathology underwent dynamic MRI. Results The study included 50 cases, comprising 34 (68%) men and 16 (32%) women. The sensitivity of dynamic study and DW imaging is 100% in detection of mass-forming and intraductal CCs. We found that apparent diffusion coefficient value of CC is lower than that of the liver and higher than that of the spleen. Relation between the apparent diffusion coefficient and CC pathological grading is evident. Conclusion DW imaging is a new effective technique in the detection and improvement of the diagnosis of CC.

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