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Subject Area

Ophthalmology

Article Type

Original Study

Abstract

Objective The aim of the study was to assess the success of endoscopic retrograde cholangiopancreatography (ERCP) for malignant obstructive jaundice using laboratory and radiological investigation. Background ERCP is a diagnostic and palliative treatment, which is used as the standard of investigation for patients with malignant obstructive jaundice; however, it failed in some patients. The prediction for success will be useful in the decision of management plan for patients with malignant obstructive jaundice and time and costs for patients and even countries. Patients and methods Collected laboratory investigation and radiological data for 20 patients presenting with malignant obstructive jaundice are included in this study, and malignant appearance of the tumor is confirmed using radiological finding or elevated tumor marker level. All patients presenting with benign stricture and duct stone are excluded from this study. Results ERCP was performed on 20 patients with malignant obstructive jaundice; the procedure was completed in 75% of patient and failed in 25% of them. P (0.0436) was significant for irresectable large-sized tumors or metastatic carcinoma. Common factors were found with failure such as advancement of the disease and comorbidities in those patients. Conclusion ERCP in patients with malignant obstructive jaundice is feasible and easy to perform in early stage. In advanced cases, other plans for biliary drainage such as surgical bypass and percutaneous transhepatic biliary drainage may be useful.

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