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Article Type

Original Study

Abstract

Objective We sought to evaluate the regional and global longitudinal strain/strain rate (SR) profiles in the right atrial (RA) wall to quantify RA function in hypertrophic cardiomyopathy. Background According to previous studies on the deformational properties of the left atrium, the systolic strain and SRs represent the atrial reservoir function and the early and late diastolic SRs show the conduit and booster functions, respectively. Patients and methods Speckle-tracking echocardiography of the RA, right ventricle, and left ventricle was acquired from apical four-chamber view in 118 hypertrophic cardiomyopathic patients and 33 healthy individuals; all had normal left ventricular systolic function. Subendocardium was traced to obtain atrial volumes, ejection fraction, velocities, and strain (ε)/SR measurements. Results Hypertrophic cardiomyopathic patients had significantly lower global and regional peak RA reservoir function (εsys, SRsys) and conduit function (SRe) compared with the controls: global εsys52.9 ± 27.9 versus 77.8 ± 31.3, SRsys2.4 ± 0.84 versus 3 ± 1.2, SRe− 2.2 ± 0.70 versus − 3.99 ± 0.73, respectively (P 0.001). RA contractile function (SRa) did not differ between the groups studied. RA ejection fraction was significantly reduced in the hypertrophic cardiomyopathy group compared with the control group (56 ± 16.7 vs. 68.9 ± 9.3, respectively, P 0.0001). Conclusion RA reservoir and conduit function as measured by strain/SR were significantly impaired, whereas contractile function showed no difference between the groups studied.

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